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22 Diet preparation In order to explore whether dietary supplementation with LC improved liver lipid metabolism through simultaneously promoting mitochondrial -oxidation and inhibiting ER stress in large yellow croaker fed with HFD, the lipid level in diets was chosen to be 18 %, in accordance with previous studies (Reference Yan, Liao and Wang38,Reference Liao, Yan and Mai40,Reference Wang, Li and Hou47,Reference Li, Xu and Lai48)

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D., del Rio-Moreno, M

10.1186/S13024-017-0150-7 Mol

Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, Souza DG, Teixeira MM (2012) NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene b4 in a murine model of gout

This suggests that basal HO-1 levels are important in the protection against inflammation and in mitigating multiple cellular responses to oxPAPC (Romanoski et al., 2011)